CIG is the UK’s leading provider of sector-specific content, publishing 15 healthcare and beauty titles including Pharmacy Magazine, Training Matters, P3Pharmacy, Independent Community Pharmacist and … The treatment of small cell lung cancer (SCLC) also advanced in 2020 with the approval of lurbinectedin (Zepzelca, Jazz/PharmaMar), an alkylating agent that is infused every 21 days. Although cancer is a large part of the designation, orphan conditions are much broader and a key component of the specialty market. “It was particularly effective in patients with brain metastases,” she said. The Orange County Register covers local news from Brea CA, including city government, crime and breaking news. Coagulation factor VIIa (recombinant)-jncw (Sevenfact, LFB S.A.) was approved to control episodes in patients with hemophilia A or B with inhibitors by bypassing the parts of the coagulation pathway that are blocked by inhibitors. Last year, specialty drugs accounted for about 48% of the drug spend, and it’s been inching up, according to the “Express Scripts 2019 Drug Trend Report” (bit.ly/3kO36EN). WASHINGTON – The Supreme Court ruled unanimously Thursday that states can regulate pharmacy benefit managers, the prescription drug "middlemen" whose actions affect 250 million … The proportion of mild or moderate bleeding episodes treated successfully with both the lower dose of 75 mcg/kg and higher dose of 225 mcg/kg (requiring no further treatment for the bleeding episode, no administration of blood products, and no increase in pain beyond 12 hours from initial dose) was approximately 86%. A new entrant in the pharmacy space may be good news for consumers, but not so much for pharmacy stocks right now. You could also check thousands of journal abstracts and full-text articles from Medline … Prescribers with questions regarding this may call 1-800-555-CLIN (1-800-555-2546), Monday through Friday, 8 a.m. to 8 p.m. Eastern time. The study also documented three severe bleeding episodes that were treated successfully with the higher dose. Stacy Giles (’92) won the … The disorders result from the buildup of defective progerin or progerin-like protein in cells. The median PFS in patients who received tucatinib plus trastuzumab-capecitabine was 7.8 months compared with 5.6 months for placebo. Just like that, 2019 is coming to a close and what a year it has … They will combine Dr. Fein’s expertise and cutting-edge analysis—such as this 2020 Economic Report on U.S. Pharmacies and Pharmacy Benefit Managers—into training videos that will offer your team a thorough grounding in crucial industry topics. 102. DEA registrants who experience theft or loss of CS would . DEA registrants who experience theft or loss of CS would . If a patient who tests positive does not have a … Marilyn Stebbins, PharmD, a UC San Francisco School of Pharmacy … A monthly magazine for independent and community pharmacists, Pharmacy Business was first published in 1998. MCL is highly aggressive following relapse, with many patients progressing following therapy. If left untreated, patients can have severe complications, including early death. www.pharmacypracticenews.com
“In the past 10 years, there’s been a significant number of new options to treat patients with several specialty conditions,” Tharaldson said at the AMCP Nexus 2020 Virtual meeting, where she highlighted several that were approved this year. “In many cases, cancers are treated more as a chronic condition. 2020… We are grieved … ... 2020. FDA issued an emergency use authorization (EUA) on Friday, December 11, for the Pfizer/BioNTech COVID-19 vaccine, which is indicated for those ages 16 years and older. For years, specialty drugs have dominated new drug approvals, and 2020 was no different. National Pharmacy Compliance News. “I didn't have to be brought up to speed on how to properly handle these vaccines,” he said. In fact, about 30% of cancer drugs have an orphan drug designation, indicating a therapy for a condition that affects fewer than 200,000 people. This year also might be the one when the specialty spend outpaces the spend for traditional medications, according to Aimee Tharaldson, PharmD, a senior clinical pharmacist, emerging therapeutics, at Express Scripts. A liquid medicine, risdiplam is administered daily at home by mouth or feeding tube. Of the patients with a response to sacituzumab govitecan-hziy, 55.6% maintained their response for six or more months and 16.7% maintained their response for 12 or more months. ABOUT. Teprotumumab-trbw is given as an IV infusion every three weeks for eight doses. Posted on: December 21, 2020; Updated on: December 21, 2020 We sat down with Gibran Ameer , 2002, CEO of VirtueTechnolgoies, Inc. and VirtueRN, LLC, to learn more about how his experiences with the University of South Carolina College of Pharmacy … © Copyright 2020, American Pharmacists Association All Rights Reserved. SUBSCRIPTION. Lonafarnib (Zokinvy, Eiger BioPharmaceuticals) was approved to reduce the risk for death from Hutchinson-Gilford progeria syndrome and for the treatment of certain processing-deficient progeroid laminopathies in patients aged 12 months and older. CVS had announced over a year ago that it would close 75 stores in 2020, after shuttering 46 in 2019, according to the analysis by the website Retail Info Systems. Through the partnership with pharmacy … “The approval of Trodelvy represents a new targeted therapy for patients living with this aggressive malignancy.”. By Nick Clarkson, Web Editor Nov 17, 2020, 11:54 am EST December 18, 2020 Amazon (NASDAQ: AMZN ) took a major step toward its pharmaceutical service … Category News index page. In 2020, Drug Channels Institute will launch a new series of online training videos. So the number of people living with cancer is growing,” Tharaldson said. CMS Pricing Transparency Rule Looms: Is Your Hospital Ready? “More broadly, because he very publicly supported health care access and affordability when he was serving in Congress, I believe that he will prove to be a strong ally for pharmacists.”. These email addresses wil only be used to send out this message. Pharmacists well understand that medication is part of the daily lives of many Americans. They will combine Dr. Fein’s expertise and cutting-edge analysis—such as this 2020 Economic Report on U.S. Pharmacies and Pharmacy … In this Motley Fool Live video recorded on Dec. 16, 2020, healthcare and cannabis bureau chief Corinne Cardina and Fool.com writer Keith Speights talk about which one of these pharmacy … New analyses of Pfizer and BioNTech's coronavirus vaccine indicate strong protection against COVID-19 within about 10 days of the first dose, much sooner than initially thought. The investigators reported an overall 60% reduction in mortality (P=0.0064). Viltolarsen (Viltepso, NS Pharma) is an antisense oligonucleotide to treat Duchenne muscular dystrophy for patients with a confirmed mutation, amenable to exon 53 skipping. In England, a 90-year-old grandmother named Maggie Keenan and an 81-year-old man named William Shakespeare have become the first and second non-trial recipients of Pfizer's COVID-19 vaccine. National Pharmacy Compliance News. In the ICARIA-MM study, isatuximab-irfc plus pom-dex demonstrated a statistically significant improvement in progression-free survival (PFS), with a median PFS of 11.53 months compared with 6.47 months with pom-dex alone (hazard ratio, 0.596; 95% CI, 0.44-0.81; P=0.0010). In the FIREFISH and SUNFISH trials, risdiplam showed clinically meaningful improvements in motor function in people with varying ages and levels of disease severity. Ripretinib (Qinlock, Deciphere), an oral TKI for the fourth-line treatment of advanced GIST, also was approved this year. The drug also is approved for RET-positive thyroid cancer and competes with pralsetinib (Gavreto, Blueprint Medicines), another oral RET inhibitor that was approved in September. December 18, 2020 NORTH FORT MYERS, Fla. – A man with a knife was taken into custody after trying to rob a pharmacy inside a North Fort Myers Publix Thursday night. August 2020 news from faculty and staff of the College of Pharmacy Duluth. Tharaldson cited several other noteworthy orphan drugs: Inebilizumab-cdon (Ulpizna, Viela Bio) and satralizumab-mwge (Enspryng, Genentech), approved for adults with neuromyelitis optica spectrum disorder (NMOSD) who are AQP4 antibody-positive. However, this pharmacy partnership is being established in anticipation that one or more COVID-19 vaccines will be authorized or approved and recommended for use in the United States before the end of 2020. Overdose Deaths Accelerating During COVID-19, Atoltivimab, maftivimab, and odesivimab-ebgn, Detect certain types of neuroendocrine tumors, Chagas disease in certain pediatric patients younger than 18 years of age, Relapsed or refractory diffuse large B-cell lymphoma, Molecularly long-chain fatty acid oxidation disorders, Diagnostic agent for patients with Alzheimer’s disease, Diagnostic imaging agent for certain patients with breast cancer, To treat advanced gastrointestinal stromal tumors, Patients with Parkinson’s disease experiencing “off” episodes, Adults with metastatic triple-negative breast cancer who received at least two prior therapies for metastatic disease, Certain patients with cholangiocarcinoma, a rare form of cancer that forms in bile ducts, Advanced unresectable or metastatic HER2-positive breast cancer, Neurofibromatosis type 1, a genetic disorder of the nervous system causing tumors to grow on nerves, Adults with Cushing’s disease who either cannot undergo pituitary gland surgery or have undergone the surgery but still have the disease, Prevent nausea and vomiting after surgery, Adults with heterozygous familial hypercholesterolemia or established atherosclerotic cardiovascular disease who require additional lowering of low-density lipoprotein cholesterol, Chronic idiopathic constipation in adults, Adults with unresectable or metastatic gastrointestinal stromal tumor. For instance, infants achieved the ability to sit without support for at least five seconds, a key motor milestone. Joseph P. Balthasar, BS ’91 & PhD ’96, Professor of Pharmaceutical Sciences, Executive Director of University Research Initiatives, and Director of the Center for Protein Therapeutics, has been named the first David and Jane Chu Endowed Chair in Drug Discovery and Development in the University at Buffalo School of Pharmacy … In the MET exon 14 population (n=97), the confirmed ORR was 68% (95% CI, 48%-84%) and 41% (95% CI, 29%-53%) among treatment-naive (n=28) and previously treated patients (n=69), respectively. Between 9% and 14% of the 8,000 cases diagnosed each year have FGFR2 mutations. Fostemsavir (Rukobia, ViiV Healthcare) is a novel oral glycoprotein 120 attachment inhibitor used with other antiretrovirals for the treatment of multidrug-resistant HIV, which affects about 10,000 U.S. patients. on July 29, 2020. The approval was based on a single arm of a multicenter trial in patients with histologically confirmed metastatic or locally advanced epithelioid sarcoma. Immunotherapy Toxicities ... Pharmacy Practice News (PPN) strives to provide health-system pharmacists with accurate, relevant and up-to-date information that improves their clinical practice. “Approximately 280,000 cases of invasive breast cancer are diagnosed annually and 17% overexpress HER2 protein,” Tharaldson said. Teprotumumab-trbw (Tepezza, Horizon Therapeutics) was the first drug approved for thyroid eye disease (Graves’ disease). Inebilizumab-cdon is a biologic that is infused every six months, and satralizumab-mwge is an interleukin-6 inhibitor given as a self-administered subcutaneous injection once monthly. reserves the right to remove without any notice comments that violate the intentions of this board. A rare form of non-Hodgkin lymphoma, MCL arises from cells in the “mantle zone” of the lymph node and predominantly affects older men. Hit the "Report Abuse" button to report comments that violate the rules and spirit of this board. Patients received tazemetostat twice daily until disease progression or unacceptable toxicity. The approval was based on data from a multicenter single-arm study in 105 adult platinum-sensitive and -resistant patients with SCLC who had disease progression after treatment with platinum-based chemotherapy. Of 74 patients with relapsed or refractory MCL in the ZUMA-2 trial, 87% responded to a single infusion. Chris Hill: It's Tuesday, November 17th. Generic Symbicort HFA inhaler FA… Somapacitan-beco (Sogroya, NovoNordisk), given as a subcutaneous injection, is a new, long-acting growth hormone analog for adults with growth hormone deficiency. Patients with hemophilia A or B also will benefit from 2020 orphan drug approvals—particularly those who are prone to inhibitor formation, which can lead to treatment failure and bleeding episodes. Brexucabtagene autoleucel (Tecartus, Kite/Gilead), a chimeric antigen receptor T-cell therapy, was approved as a one-time infusion for mantle cell lymphoma (MCL), and tafasitamab-cxix (Monjuvi, MorphoSys/Incyte) was approved as an IV infusion for large B-cell lymphoma. For all of these reasons, Drug Store News has named Rite Aid its 2020 Pharmacy Innovator of the Year. Tafasitamab-cxix should be used with lenalidomide and given on days 1 and 15 of a 28-day cycle after induction therapy. Amazon has filed to trademark “Amazon Pharmacy” in Canada, the U.K. and Australia, signaling a potential move into selling prescription drugs outside of the U.S. The Vaccines and Related Biological Products Advisory Committee is likely to recommend today that FDA approve a COVID-19 vaccine developed by Pfizer and BioNTech. “Clinical trials showed ... almost 85% of patients experiencing tumor shrinkage with this targeted drug,” said Richard Pazdur, MD, the director of the FDA’s Oncology Center of Excellence. About 8% of patients who have this dystrophy have a confirmed mutation amenable to exon 53 skipping. FDA's vaccine advisory panel on Thursday voted 17-4 to recommend regulatory emergency authorization of Pfizer and BioNTech's COVID-19 vaccine, which the agency is expected to push forward within a matter of days. Capmatinib (Tabrecta, Novartis) is an oral TKI approved for adults with metastatic or inoperable non-small cell lung cancer (NSCLC) with a mesenchymal-epithelial transition (MET) exon 14 skipping mutation. Isatuximab-irfc was approved as an IV infusion given once weekly for four weeks, then every other week. The approval was based on the ongoing single-arm, open-label ZUMA-2 trial. About Operation Warp Speed (OWS): Early clinical evidence indicates durable remissions in later lines of therapy, Wang added. G. Zumach, Kerry K. Fierke , associate professor, and W. D. Maxwell had their article, “ Utilizing a virtual symposium to engage membership ,” published in The Mortar Board , a publication of the International Pharmaceutical Federation Academic Pharmacy … Approval was supported by a clinical trial showing that more than half of patients had undetectable viral loads with the addition of fostemsavir. ADVERTISEMENT The agency started the year by approving avapritinib (Ayvakit, Blueprint Medicines), … Other specialty cancer drugs approved in 2020 were tazemetostat (Tazverik, Epizyme), an oral dimethyltransferase inhibitor for inoperable epithelioid sarcoma, and isatuximab-irfc (Sarclisa, Sanofi), an IV drug for relapsed/refractory multiple myeloma. CDC’s Advisory Committee on Immunization Practices (ACIP) gave the vaccine its official recommendation on Saturday, December 12, and finalized its endorsement to prioritize COVID-19 vaccination for health care workers—including pharmacists—and residents of long-term-care facilities with the limited supply that will be available initially. The FDA approved sacituzumab govitecan-hziy based on a clinical trial of 108 patients with metastatic TNBC who had received at least two prior treatments for metastatic disease. The St. Luke's PGY2 Pharmacotherapy residency program led by Heather Blue, assistant professor, … Disclaimer: This board is intended for non-commercial reader comments. Novartis estimated that up to 5,000 patients will be candidates annually for this treatment, which is the first drug to be approved for NSCLC caused by the MET mutation. Posted on: December 21, 2020; Updated on: December 21, 2020 We sat down with Gibran Ameer , 2002, CEO of VirtueTechnolgoies, Inc. and VirtueRN, LLC, to learn more about how his experiences with the University of South Carolina College of Pharmacy shaped his career. Posted on: October 21, 2020. The biologic is used with pomalidomide and dexamethasone (pom-dex) to treat adults with multiple myeloma who have received at least two prior therapies. A link to this article will be included in this email. Weighing Risks Vs Benefits. WASHINGTON – The Supreme Court ruled unanimously Thursday that states can regulate pharmacy benefit managers, the prescription drug "middlemen" … November. Efficacy is about 52% with the first dose, then reaches about 95% with the second, the evidence shows. > news > The Ten Pharmacy Trends to Watch Out For in 2020. In clinical trials, the life span of patients with Hutchinson-Gilford progeria syndrome who were treated with lonafarnib increased by an average of three months through the first three years of treatment, and by an average of 2.5 years through the maximum follow-up of 11 years. MAJ Joseph Remesz-Guerrette, PharmD, U.S. Army, has had plenty of experience in the storage and handling of pharmaceuticals over his decade or so in pharmacy. 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